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Proteins and Peptides

Cynomolgus IL-23 R Protein, His Tag (MALS & SPR verified)

Product Sizes
100 ug
£424.00
ILR-C52H7-100UG
1 mg
£2768.00
ILR-C52H7-1MG
About this Product
SKU:
ILR-C52H7
Buffer:
PBS
Extra Details:
Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Immunogen:
IL-23 R
Molecular Weight:
40.0 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins