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Proteins and Peptides

Human IL-18BP Protein, Fc Tag (MALS verified)

Product Sizes
200 ug
£307.00
ILP-H5253-200UG
1 mg
£1154.00
ILP-H5253-1MG
About this Product
SKU:
ILP-H5253
Additional Names:
IL18BP|IL18BPa|Tadekinig-alfa
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
Immunogen:
IL-18BP
Molecular Weight:
44.3 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-18BP, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-18 Protein, premium grade (Cat. No. IL8-H5114) at 5 ug/mL (100 uL/well) can bind Human IL-18BP, Fc Tag (Cat. No. ILP-H5253) with a linear range of 0.6-20 ng/mL (QC tested).