Human IL-18BP Protein, His Tag, low endotoxin (MALS & SPR verified)
Product Sizes
200 ug
£265.00
ILP-H5222-200UG
1 mg
£1090.00
ILP-H5222-1MG
About this Product
- SKU:
- ILP-H5222
- Additional Names:
- IL18BP|IL18BPa|Tadekinig-alfa
- Buffer:
- PBS
- Extra Details:
- Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
- Immunogen:
- IL-18BP
- Molecular Weight:
- 18.5 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
