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Proteins and Peptides

Human IL-1 RI Protein, Fc Tag (MALS verified)

Product Sizes
100 ug
£289.00
ILI-H5253-100UG
1 mg
£1867.00
ILI-H5253-1MG
About this Product
SKU:
ILI-H5253
Buffer:
PBS
Extra Details:
IL1R1 also know as Interleukin-1 receptor type 1, is the receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells
Immunogen:
IL-1 RI
Molecular Weight:
63.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-1 RI Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-1 beta, His Tag (Cat. No. ILB-H51H3) at 5 ug/mL (100 uL/well) can bind Human IL-1 RI Protein, Fc Tag (Cat. No. ILI-H5253) with a linear range of 2-78 ng/mL (QC tested).