Cynomolgus IL-2 R gamma / CD132 Protein, His Tag (MALS verified)
Product Sizes
100 ug
£318.00
ILG-C52H8-100UG
1 mg
£3191.00
ILG-C52H8-1MG
About this Product
- SKU:
- ILG-C52H8
- Buffer:
- PBS
- Extra Details:
- IL-2R is a heterotrimeric protein binds and responds to the cytokine IL-2. Three distinct chains of IL-2R, termed as A Alpha, B Beta and G Gamma, which are non-covalently associated are identified. The A Alpha and B Beta chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the G Gamma chain, along with the B Beta subunit. The A Alpha chain of the IL-2R can bind to the B Beta chain before receptor interaction with IL-2. The G Gamma chain alone has a very weak affinity for IL-2, but after the ligand is bound to the A Alpha/B Beta heterodimer, the G Gamma chain becomes recruited to the complex to form a very stable macromolecular quaternary ligand/receptor complex. Interleukin-2 receptor subunit gamma (IL2RG), also known as cytokine receptor common subunit gamma, CD antigen CD132, gammaC, p64, which belongs to the type I cytokine receptor family or type 5 subfamily. IL2RG is located on the surface of immature blood-forming cells in bone marrow. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell-negative (XSCID).
- Immunogen:
- IL-2 R gamma
- Molecular Weight:
- 29.4 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
