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Proteins and Peptides

Human IL-17F Protein, His Tag, low endotoxin (MALS verified)

Product Sizes
20 ug
£183.00
ILF-H5244-20UG
50 ug
£401.00
ILF-H5244-50UG
1 mg
£3068.00
ILF-H5244-1MG
About this Product
SKU:
ILF-H5244
Additional Names:
Cytokine ML-1|IL-17F|Interleukin-17F
Buffer:
PBS
Extra Details:
Interleukin-17F (IL17F) is also known as Interleukin-24 (IL24), Cytokine ML-1, is a secreted disulfide-linked homodimer which belongs to the IL-17 family. There are at least six members of the IL-17 family in humans and in mice: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25) and IL-17F (also called IL-24). IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17F / IL-24 is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL17F / Interleukin-24 stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. IL17F / IL-24 stimulates PBMC and T-cell proliferation and Inhibits angiogenesis. Defects in IL17F are the cause of familial candidiasis type 6 (CANDF6).
Immunogen:
IL-17F
Molecular Weight:
16.8 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-17F, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-17F, His Tag (Cat. No. ILF-H5244) at 5 ug/mL (100 uL/well) can bind Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) with a linear range of 2-39 ng/mL (QC tested).
Immobilized Human IL-17F, His Tag (Cat. No. ILF-H5244) at 2 ug/mL (100 uL/well) can bind Human IL-17 RC, Fc Tag with a linear range of 0.016-0.25 ug/mL (Routinely tested).