Biotinylated Human IL-17C Protein, His,Avitag[TM] (MALS verified)
Product Sizes
25 ug
£377.00
ILC-H82E5-25UG
200 ug
£1614.00
ILC-H82E5-200UG
About this Product
- SKU:
- ILC-H82E5
- Additional Names:
- Cytokine CX2|IL-17C|IL17C
- Buffer:
- PBS, 0.5 M Arginine, pH7.4
- Conjugate:
- Biotin
- Extra Details:
- Interleukin-17C(IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL-17C binds to IL-17 RE with high affinity and to IL-17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.
- Immunogen:
- IL-17C
- Molecular Weight:
- 23.3 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
