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Proteins and Peptides

Human IL-17 RA&IL-17 RC Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Product Sizes
100 ug
£377.00
ILC-H5257-100UG
1 mg
£2703.00
ILC-H5257-1MG
About this Product
SKU:
ILC-H5257
Additional Names:
CD217 & IL-17 RC|IL-17 RA & IL-17 RC|IL-17RA & IL-17RC
Buffer:
PBS
Extra Details:
Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.
Immunogen:
IL-17 RA & IL-17 RC
Molecular Weight:
60.0 kDa (IL-17 RA) & 75.7 kDa (IL-17 RC)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-17A&IL-17F Heterodimer Protein, His Tag&Strep II Tag at 2 ug/mL (100 uL/well) can bind Human IL17RA & IL17RC Protein, Fc Tag&Fc Tag (Cat. No. ILC-H5257) with a linear range of 1-20 ng/mL (QC tested).
Immobilized Human IL17A, Tag Free at 2 ug/mL (100 uL/well) can bind Human IL17RA & IL17RC Protein, Fc Tag&Fc Tag (Cat. No. ILC-H5257) with a linear range of 0.6-10 ng/mL (Routinely tested).