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Biotinylated Mouse IL-23 alpha & IL-12 beta Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)

Product Sizes
25 ug
£483.00
ILB-M82W3-25UG
200 ug
£2102.00
ILB-M82W3-200UG
About this Product
SKU:
ILB-M82W3
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL23A & IL12B
Molecular Weight:
23.2 kDa & 35.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Mouse IL23A & IL12B Heterodimer Protein, His,Avitag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Mouse IL-23R, Fc Tag (Cat. No. ILR-M5251) at 5 ug/mL (100 uL/well) can bind Biotinylated Mouse IL23A & IL12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-M82W3) with a linear range of 0.005-0.156 ug/mL (QC tested).
Immobilized Human IL-12 R beta 1, Fc Tag (Cat. No. ILB-H5255) at 5 ug/mL (100 uL/well) can bind Biotinylated Mouse IL23A & IL12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-M82W3) with a linear range of 0.002-0.313 ug/mL (Routinely tested).