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Proteins and Peptides

Human IL-23 alpha&Rat IL-12 beta Heterodimer Protein, His Tag&Tag Free, Ultra Low Endotoxin (MALS verified)

Product Sizes
100 ug
£519.00
ILB-HR52W4-100UG
1 mg
£4098.00
ILB-HR52W4-1MG
About this Product
SKU:
ILB-HR52W4
Buffer:
PBS
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL23A & IL12B
Molecular Weight:
20.6 kDa & 35.9 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) at 5 ug/mL (100 uL/well) can bind Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-HR52W4) with a linear range of 0.02-0.625 ug/mL (QC tested).
Immobilized Human IL-23A&Rat IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-HR52W4) at 5 ug/mL (100 uL/well) can bind Human IL-12 R beta 1, Fc Tag with a linear range of 0.1-16 ng/mL (QC tested).