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Biotinylated Human IL-23 alpha&IL-12 beta Heterodimer Protein, His,Avitag[TM]&Tag Free (MALS verified)

Product Sizes
25 ug
£377.00
ILB-H82W6-25UG
200 ug
£1614.00
ILB-H82W6-200UG
About this Product
SKU:
ILB-H82W6
Additional Names:
IL-23 alpha & IL-12 beta
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL23A & IL12B
Molecular Weight:
21.9 kDa (IL23A) & 34.7 kDa (IL12B)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human IL-23 alpha&IL-12 beta Heterodimer Protein, His,Avitag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Anti-p19 subunit of IL23 (Anti-IL23A) MAb, Human IgG1 at 2 ug/mL (100 uL/well) can bind Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) with a linear range of 1.2-19.5 ng/mL (QC tested).
Immobilized Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free (Cat. No. ILB-H82W6) at 2 ug/mL (100 uL/well) on streptavidin precoated (0.2 ug/well) plate, can bind Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) with a linear range of 0.4-6 ng/mL (Routinely tested).