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Biotinylated Human IL-17B Protein, Fc,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£377.00
ILB-H82F1-25UG
200 ug
£1466.00
ILB-H82F1-200UG
About this Product
SKU:
ILB-H82F1
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
IL-17B is a member of IL17 famaily, was originally described as a proinflammatory cytokine. IL-17B is produced by neutrophils and potentiates TNF-A Alpha effect on the production of cytokines and chemokines, such as IL-6, G-CSF, and CCL20, known to control immune cell trafficking to inflamed tissues. Interestingly, although IL-17B and IL-17E (IL-25) share a common receptor, IL-17RB, IL-17B, and IL-17E deficiency lead to opposite results in a model of acute colitis induced by dextran sulfate sodium. IL-17B inhibits IL-17E binding to IL-17RA- IL-17RB complexes on epithelial cells, and limits IL-17E-induced IL-6 production by colon epithelial cells.
Immunogen:
IL-17B
Molecular Weight:
45.8 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein