Biotinylated Human IL-12 R beta 2 Protein, His,Avitag[TM] (MALS verified)
Product Sizes
25 ug
£377.00
ILB-H82E4-25UG
200 ug
£1466.00
ILB-H82E4-200UG
About this Product
- SKU:
- ILB-H82E4
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12RB2 is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. IL-12B2 gene acts as tumor suppressor in human acute and chronic B-cell leukemias/lymphomas, IL-12R beta 2 directly restrains multiple myeloma cell growth, and targeting of IL-12 to tumor cells holds promise as new therapeutic strategy.
- Immunogen:
- IL-12 R beta 2
- Molecular Weight:
- 71.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
