Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free (MALS verified)

Product Sizes
50 ug
£389.00
ILB-H52W5-50UG
1 mg
£3904.00
ILB-H52W5-1MG
About this Product
SKU:
ILB-H52W5
Additional Names:
IL-23 alpha & IL-12 beta
Buffer:
PBS
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL23A & IL12B
Molecular Weight:
19.5 kDa (IL23A) & 34.7 kDa (IL12B)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-H52W5) at 2 ug/mL (100 uL/well) can bind Monoclonal Anti-Human IL23A&IL12B P40 domain Antibody, Human IgG1 with a linear range of 0.1-1.25 ng/mL (QC tested).
Immobilized Human IL-23 R, Fc Tag (Cat. No. ILR-H5254) at 10 ug/mL (100 uL/well) can bind Human IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-H52W5) with a linear range of 20-78 ng/mL (Routinely tested).