Human IL-37b / IL-1F7b Protein, His Tag
Product Sizes
50 ug
£265.00
ILB-H5141-50UG
500 ug
£1408.00
ILB-H5141-500UG
About this Product
- SKU:
- ILB-H5141
- Additional Names:
- FIL1Z|IL1F7|IL1H4|IL1RP1|IL37
- Buffer:
- PBS
- Extra Details:
- Interleukin-1 family member 7 (IL1F7b) ,a member of the IL-1 family, is aslo known as interleukin-37, interleukin-1 homolog 4 (IL-1H4), interleukin-1 zeta (IL-1 zeta) and interleukin-1-related protein, which can interact with SMAD3 and bind to IL18R1, but not to IL1R1, with lower affinity than IL18. IL1F7b is a suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Therefore,IL1F7b can suppress, or reduce, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spare anti-inflammatory cytokines. Furthermore,IL1F7b can also inhibit dendritic cell activation.
- Immunogen:
- IL-37
- Molecular Weight:
- 20.3 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
