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Proteins and Peptides

Cynomolgus IL-23 alpha&Mouse IL-12 beta Heterodimer Protein, His Tag&Tag Free (MALS verified)

Product Sizes
50 ug
£377.00
ILB-CM52W8-50UG
1 mg
£4098.00
ILB-CM52W8-1MG
About this Product
SKU:
ILB-CM52W8
Additional Names:
IL-23 alpha & IL-12 beta
Buffer:
PBS
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL23A & IL12B
Molecular Weight:
20.3 kDa (IL23A) & 35.8 kDa (IL12B)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus IL-23A&Mouse IL-12B Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Biotinylated Human IL-23 R, Fc,Avitag (Cat. No. ILR-H82F3) at 1 ug/mL (100 uL/well) on Streptavidin precoated (0.5 ug/well) plate can bind Cynomolgus IL-23A & Mouse IL-12B Heterodimer Protein, His Tag&Tag Free (Cat. No. ILB-CM52W8) with a linear range of 0.03-0.25 ug/mL (QC tested).