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Biotinylated Human IL-15 R alpha / CD215 Protein, Fc,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£377.00
ILA-H82F4-25UG
200 ug
£1614.00
ILA-H82F4-200UG
About this Product
SKU:
ILA-H82F4
Additional Names:
CD215|IL-15 R alpha|IL-15R-alpha|IL-15RA|IL15RA
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Conjugate:
Biotin
Extra Details:
IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor A Alpha fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
Immunogen:
IL-15 R alpha
Molecular Weight:
46.6 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human IL-15 R alpha, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-15, premium grade (Cat. No. IL5-H4117) at 2 ug/mL (100 uL/well) can bind Biotinylated Human IL-15 R alpha, Fc,Avitag (Cat. No. ILA-H82F4) with a linear range of 2-39 ng/mL (QC tested).
Immobilized Mouse IL-15, Fc Tag (Cat. No. IL5-M5255) at 2 ug/mL (100 uL/well) can bind Biotinylated Human IL-15 R alpha, Fc,Avitag (Cat. No. ILA-H82F4) with a linear range of 10-156 ng/mL (Routinely tested).