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Biotinylated Human IL-2 R alpha / CD25 Protein, His,Avitag[TM], premium grade

Product Sizes
25 ug
£377.00
ILA-H82E6-25UG
200 ug
£1614.00
ILA-H82E6-200UG
About this Product
SKU:
ILA-H82E6
Additional Names:
CD25|IL-2-RA|IL2-RA|IL2RA|p55
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
Immunogen:
IL-2 R alpha
Molecular Weight:
25.4 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human IL-2 R alpha, His,Avitag, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-2 Protein, Fc Tag (Cat. No. IL2-H5269) at 5 ug/mL (100 uL/well) can bind Biotinylated Human IL-2 R alpha, His,Avitag, premium grade (Cat. No. ILA-H82E6) with a linear range of 0.06-10 ng/mL (QC tested).