Biotinylated Human IL-15 R alpha Protein, His,Avitag[TM] (MALS verified)
Product Sizes
25 ug
£377.00
ILA-H82E5-25UG
200 ug
£1466.00
ILA-H82E5-200UG
About this Product
- SKU:
- ILA-H82E5
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor A Alpha fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
- Immunogen:
- IL-15 R alpha
- Molecular Weight:
- 22 kda
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
