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Proteins and Peptides

Human IL-23A Protein, Fc Tag

Product Sizes
100 ug
£360.00
ILA-H525H-100UG
1 mg
£2385.00
ILA-H525H-1MG
About this Product
SKU:
ILA-H525H
Buffer:
PBS
Extra Details:
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Immunogen:
IL-23A
Molecular Weight:
45.1 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-23A Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-23A Protein, Fc Tag (Cat. No. ILA-H525h) at 1 ug/mL (100 uL/well) can bind Mirikizumab with a linear range of 0.002-0.25 ug/mL (QC tested).