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Proteins and Peptides

Mouse IL-18 Protein, His Tag

Product Sizes
100 ug
£366.00
IL8-M51H3-100UG
1 mg
£2391.00
IL8-M51H3-1MG
About this Product
SKU:
IL8-M51H3
Buffer:
PBS
Extra Details:
Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-gamma (IFN-gamma) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL-12. IL-18 also functions in developmental regulation of T-lymphocyte helper type I cells and in Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. It acts by inducing heterodimerization of the two subunits of its receptor, IL-18RAlpha and IL-18RBeta shows structural similarity to IL-1.
Immunogen:
IL-18
Molecular Weight:
20.0 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Mouse IL-18 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Recombinant Mouse IL-18 BPd Fc Chimera Protein, CF at 5 ug/mL (100 uL/well) can bind Mouse IL-18 Protein, His Tag (Cat. No. IL8-M51H3) with a linear range of 0.2-10 ng/mL (QC tested).