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Proteins and Peptides

Human IL-36 beta / IL-1F8 Protein, Tag Free (MALS verified)

Product Sizes
100 ug
£318.00
IL8-H5119-100UG
1 mg
£2320.00
IL8-H5119-1MG
About this Product
SKU:
IL8-H5119
Buffer:
PBS
Extra Details:
The IL-36 subfamily of cytokines is the most diverse, including three agonists(IL-36A Alpha, IL-36B Beta, and IL-36G Gamma), one antagonist(IL-36Ra), one cognate receptor(IL-36R) and one accessory protein(IL-1RAcP). The receptor activation follows a two-step mechanism in that the agonist first binds to IL-36R and the resulting binary complex recruits IL-1RAcP. IL-36B Beta that binds to and signals through the IL-36R which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Appropriately balanced IL-36 signaling is a critical determinant of skin and lung health.
Immunogen:
IL-36 beta
Molecular Weight:
17.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-36 beta Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-36 beta Protein, Tag Free (Cat. No. IL8-H5119) at 5 ug/mL (100 uL/well) can bind Human IL-1 Rrp2, Fc Tag (Cat. No. IL2-H5254) with a linear range of 0.078-10 ug/mL (QC tested).