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Proteins and Peptides

Human IL-18 Protein, Research Grade

Product Sizes
20 ug
£177.00
IL8-H5116-20UG
50 ug
£224.00
IL8-H5116-50UG
1 mg
£2167.00
IL8-H5116-1MG
About this Product
SKU:
IL8-H5116
Buffer:
PBS
Extra Details:
Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-G Gamma (IFN-G Gamma) production from T helper type 1 (Th1) cells and natural killer (NK) cells, particularly in the presence of IL-12. IL-18 also participates in the developmental regulation of Th1 cells and mediates Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for the treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. IL-18 exerts its biological functions by inducing heterodimerization of the two subunits of its receptor, IL-18RA Alpha and IL-18RB Beta. These subunits share structural homology with members of the IL-1 receptor superfamily.
Immunogen:
IL-18
Molecular Weight:
18.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-18 Protein, Research Grade on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human IL-18 Protein, Research Grade (Cat. No. IL8-H5116) at 5 ug/mL (100 uL/well) can bind Human IL-18BP, Fc Tag (Cat. No. ILP-H5253) with a linear range of 2-78 ng/mL (QC tested).