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Proteins and Peptides

Human IL-6 R alpha & IL-6 Protein, His Tag (HPLC verified)

Product Sizes
100 ug
£442.00
IL6-H52H4-100UG
1 mg
£3120.00
IL6-H52H4-1MG
About this Product
SKU:
IL6-H52H4
Buffer:
PBS
Extra Details:
Interleukin 6 (IL-6) is also known as HGF, BSF2, HSF and IFNB2, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts, endothelial cells, et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic, lupus erythematosus, prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood. Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.
Immunogen:
IL-6 R alpha & IL-6
Molecular Weight:
65.0 kDa & 20.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-6 R alpha & IL-6 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human gp130 Protein, Fc Tag (Cat. No. ILT-H5254) at 5 ug/mL (100 uL/well) can bind Human IL-6 R alpha & IL-6 Protein, His Tag (Cat. No. IL6-H52H4) with a linear range of 1-20 ng/mL (QC tested).