Mouse IL-3 Protein, His Tag (MALS & SPR verified)
Product Sizes
100 ug
£413.00
IL3-M52H8-100UG
1 mg
£2703.00
IL3-M52H8-1MG
About this Product
- SKU:
- IL3-M52H8
- Additional Names:
- IL3|Interleukin-3|MCGF|MGC79398|MGC79399|MULTI-CSF
- Buffer:
- PBS
- Extra Details:
- Interleukin 3 is also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. The IL-3 receptor is a heterodimer of the IL-3 specific A Alpha-chain and the common B Beta-chain, B Betac, which is also used by GM-CSF and IL-5. [3] Binding of IL-3 can also involve substitution of the B Betac by a B BetaIL-3-chain that appears to be specific for IL-3 . Binding of IL-3 to its cognate receptor(s) induces activation of Jak2, phosphorylation of multiple Stats, and the PI3K/Akt pathway. IL-3 may play an important role in the development of airway inflammation associated with asthma. The human IL-3 gene encodes a protein 152 amino acids long, and the naturally occurring IL-3 is glycosylated. The human IL-3 gene is located on chromosome 5, only 9 kilobases from the GM-CSF gene, and its function is quite similar to GM-CSF.
- Immunogen:
- IL-3
- Molecular Weight:
- 17.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
