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Proteins and Peptides

Mouse IL-13 Protein, His Tag (MALS verified)

Product Sizes
50 ug
£413.00
IL3-M5249-50UG
500 ug
£2108.00
IL3-M5249-500UG
About this Product
SKU:
IL3-M5249
Additional Names:
ALRH|BHR1|IL13|Interleukin-13|MGC116786|MGC116788|MGC116789|P600
Buffer:
PBS
Extra Details:
Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4RA Alpha) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.
Immunogen:
IL-13
Molecular Weight:
14.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Mouse IL-13, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Mouse IL-13, His Tag (Cat. No. IL3-M5249) at 5 ug/mL (100 uL/well) can bind Mouse IL-13RA1, Fc Tag (Cat. No. IL1-M5258) with a linear range of 0.08-2 ng/mL (QC tested).
Immobilized Mouse IL-13, His Tag (Cat. No. IL3-M5249) at 5 ug/mL (100 uL/well) can bind Human IL-13 R alpha 2 Protein, Fc Tag (Cat. No. IL2-H5256) with a linear range of 0.2-10 ng/mL (Routinely tested).