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Biotinylated Human IL-33 Protein, His,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£377.00
IL3-H82H5-25UG
200 ug
£1614.00
IL3-H82H5-200UG
About this Product
SKU:
IL3-H82H5
Additional Names:
C9ORF26|DKFZp586H0523|DV27|DVS27|IL1F11|IL33|NFEHEV|NFHEV|RP11-575C20.2
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-K KappaB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
Immunogen:
IL-33
Molecular Weight:
21.9 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human IL-33, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-1RL1, Fc Tag (Cat. No. IL1-H5250) at 5 ug/mL (100 uL/well) can bind Biotinylated Human IL-33, His,Avitag (Cat. No. IL3-H82H5) with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Biotinylated Human IL-33, His,Avitag (Cat. No. IL3-H82H5) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Tozorakimab with a linear range of 0.2-8 ng/mL (Routinely tested).