Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Cynomolgus IL-33 Protein, His Tag (MALS verified)

Product Sizes
50 ug
£377.00
IL3-C5245-50UG
1 mg
£3044.00
IL3-C5245-1MG
About this Product
SKU:
IL3-C5245
Additional Names:
C9ORF26|DKFZp586H0523|DV27|DVS27|IL1F11|IL33|NFEHEV|NFHEV|RP11-575C20.2
Buffer:
PBS
Extra Details:
Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-K KappaB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
Immunogen:
IL-33
Molecular Weight:
20.2 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Cynomolgus IL-33, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Cynomolgus IL-33, His Tag (Cat. No. IL3-C5245) at 5 ug/mL (100 uL/well) can bind Human IL-1RL1, Fc Tag (Cat. No. IL1-H5250) with a linear range of 2-78 ng/mL (QC tested).