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Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag[TM]&Flag Tag (MALS verified)

Product Sizes
25 ug
£377.00
IL2-H8210-25UG
200 ug
£1614.00
IL2-H8210-200UG
About this Product
SKU:
IL2-H8210
Additional Names:
IL12|Interleukin-12|p70
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-G Gamma and TNF-A Alpha from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-G Gamma. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.
Immunogen:
IL-12B & IL-12A
Molecular Weight:
38.3 kDa & 23.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human IL-12B&IL-12A Heterodimer, His,Avitag&Flag Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-12 R beta 1, Fc Tag (Cat. No. ILB-H5255) at 5 ug/mL (100 uL/well) can bind Biotinylated Human IL-12B&IL-12A Heterodimer, His,Avitag&Flag Tag (Cat. No. IL2-H8210) with a linear range of 0.2-2.5 ug/mL (QC tested).
Immobilized Biotinylated Human IL-12B&IL-12A Heterodimer Protein, His,Avitag&Flag Tag (Cat. No. IL2-H8210) at 1 ug/mL (100 uL/well)on streptavidin precoated (0.5 ug/well) plate. can bind Monoclonal Anti-Human IL23A&IL12B P40 domain Antibody, Human IgG1 with a linear range of 0.2-1 ng/mL (Routinely tested).