Human IL-1 RII / CD121b Protein, Fc Tag
Product Sizes
100 ug
£289.00
IL2-H4256-100UG
1 mg
£1867.00
IL2-H4256-1MG
About this Product
- SKU:
- IL2-H4256
- Additional Names:
- CD121b|CDw121b|IL1R2|IL1RB
- Buffer:
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
- Extra Details:
- Interleukin-1 receptor type 2 (IL1R2) is also known as CD121 antigen-like family member B (CDw121b), IL-1 type II receptor, Interleukin-1 receptor type II, belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R2 is non-signaling receptor for IL1A, IL1B and IL1RN, reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
- Immunogen:
- IL-1 RII
- Molecular Weight:
- 63.9 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
