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Proteins and Peptides

Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag (MALS verified)

Product Sizes
20 ug
£183.00
IL2-H4210-20UG
50 ug
£401.00
IL2-H4210-50UG
1 mg
£4793.00
IL2-H4210-1MG
About this Product
SKU:
IL2-H4210
Additional Names:
IL12|Interleukin-12|p70
Buffer:
PBS
Extra Details:
Interleukin 12 (IL12) is also known as p70, and is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine, containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of IFN-G Gamma and TNF-A Alpha from T cells and NK cells, and reduces IL-4 mediated suppression of IFN-G Gamma. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity, which means it can block the formation of new blood vessels.
Immunogen:
IL-12B & IL-12A
Molecular Weight:
36.6 kDa (IL12B) and 23.8 kDa (IL12A)
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag (Cat. No. IL2-H4210) at 0.5 ug/mL (100 uL/well) can bind Monoclonal Anti-Human IL23A&IL12B P40 domain Antibody, Human IgG1 with a linear range of 0.05-2 ng/mL (QC tested).
Immobilized Biotinylated Human IL-12 R beta 1, Fc,Avitag (Cat. No. ILB-H82F7) at 1 ug/mL (100 uL/well) on Streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate, can bind Human IL-12B&IL-12A Heterodimer Protein, His Tag&Flag Tag (Cat. No. IL2-H4210) with a linear range of 0.039-0.625 ug/mL (Routinely tested).