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Proteins and Peptides

Human IL-31 Protein, His Tag, low Endotoxin (MALS verified)

Product Sizes
100 ug
£424.00
IL1-H5247-100UG
1 mg
£2874.00
IL1-H5247-1MG
About this Product
SKU:
IL1-H5247
Additional Names:
IL-31|IL31|Interleukin-31
Buffer:
PBS
Extra Details:
IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor B Beta (OSMRB Beta) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.
Immunogen:
IL-31
Molecular Weight:
17.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human IL-31, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human IL-31, His Tag (Cat. No. IL1-H5247) at 1 ug/mL (100 uL/well) can bind Human IL-31 RA, Fc Tag (Cat. No. ILA-H5256) with a linear range of 0.02-0.625 ug/mL (QC tested).