Human IDO1 Protein, His Tag (active enzyme, MALS verified)
Product Sizes
100 ug
£972.00
ID1-H5143-100UG
1 mg
£3250.00
ID1-H5143-1MG
About this Product
- SKU:
- ID1-H5143
- Buffer:
- 20 mM Tris, 300 mM NaCl, pH7.5
- Extra Details:
- This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
- Immunogen:
- IDO1
- Molecular Weight:
- 47.2 kda
- Physical State:
- Liquid
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
