Human HMGB1 Protein, Mouse IgG2a Fc Tag, low endotoxin
Product Sizes
100 ug
£395.00
HM1-H5255-100UG
1 mg
£2703.00
HM1-H5255-1MG
About this Product
- SKU:
- HM1-H5255
- Additional Names:
- HMG1|HMG3|HMGB1|SBP-1
- Buffer:
- 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
- Extra Details:
- High-mobility group protein B1 (HMGB1) is also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. The mechanism of inflammation and damage is binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy.
- Immunogen:
- HMGB1
- Molecular Weight:
- 51.6 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
