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Proteins and Peptides

Human HMGB1 Protein, His Tag, low endotoxin

Product Sizes
100 ug
£407.00
HM1-H5220-100UG
1 mg
£2838.00
HM1-H5220-1MG
About this Product
SKU:
HM1-H5220
Additional Names:
HMG1|HMG3|HMGB1|SBP-1
Buffer:
PBS
Extra Details:
High-mobility group protein B1 (HMGB1) is also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. The mechanism of inflammation and damage is binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy.
Immunogen:
HMGB1
Molecular Weight:
26.8 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human HMGB1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human HMGB1, His Tag (Cat. No. HM1-H5220) at 5 ug/mL (100 uL/well) can bind Human RAGE, Fc Tag with a linear range of 0.078-2.5 ug/mL (Routinely tested).