APC-Labeled Human HLA-A*02:01&B2M&hTERT (ILAKFLHWL) Tetramer Protein
Product Sizes
25 ug
£424.00
HLT-HA2H7-25UG
200 ug
£2426.00
HLT-HA2H7-200UG
About this Product
- SKU:
- HLT-HA2H7
- Buffer:
- PBS, 1% BSA, pH7.4
- Conjugate:
- APC
- Extra Details:
- hTERT (human Telomerase Reverse Transcriptase), the catalytic subunit of telomerase, maintains telomere length to drive tumor cells' unlimited proliferation. It is highly expressed in ~85-90% of cancers but silenced in most normal somatic cells. The peptide ILAKFLHWL (from hTERT residues 540-548) acts as a tumor-specific antigen. It binds to MHC class I molecule HLA-A0201 to form a surface complex on tumors, activating cytotoxic T lymphocytes (CTLs). The Human HLA-A*0201 hTERT (ILAKFLHWL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and ILAKFLHWL peptide of the hTERT.
- Immunogen:
- HLA-A*0201 & B2M & hTERT (ILAKFLHWL)
- Molecular Weight:
- 36.3 kDa and 11.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
