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Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Monomer, MALS verified)

Product Sizes
25 ug
£185.00
HLT-H82E3-25UG
200 ug
£731.00
HLT-H82E3-200UG
About this Product
SKU:
HLT-H82E3
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
The peptide RISTFKNWPK, derived from a survivin mutant, is presented by the HLA-A*03:01/B Beta2m complex and serves as a promising neoantigen target. Its presentation enables cytotoxic T lymphocytes (CTLs) to recognize and attack tumor cells overexpressing this mutated survivin variant, which is often associated with cancer cell survival and therapy resistance, offering a potential avenue for specific immunotherapy.
Immunogen:
HLA-A*0301 & B2M & Survivin Mut (RISTFKNWPK)
Molecular Weight:
36.1 kDa and 11.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 ug/mL (100 uL/well) can bind Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) with a linear range of 0.1-4 ng/mL (QC tested).
Immobilized Biotinylated Human HLA-A*03:01&B2M&Survivin Mut (RISTFKNWPK) Complex Protein (Cat. No. HLT-H82E3) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.2-3 ng/mL (Routinely tested).