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Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Monomer, MALS verified)

Product Sizes
25 ug
£180.00
HLR-H82E2-25UG
200 ug
£707.00
HLR-H82E2-200UG
About this Product
SKU:
HLR-H82E2
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
The peptide VVVGARGVGK, derived from the KRAS G12R mutation and presented by the HLA-A*11:01/B Beta2-microglobulin (B Beta2m) complex, is a pivotal antigenic target in antitumor immunity. This complex plays a crucial role by activating specific cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells harboring the KRAS G12R mutation.
Immunogen:
HLA-A*1101 & B2M & KRASG12R (VVVGARGVGK)
Molecular Weight:
36.0 kDa and 11.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Cat. No. HLR-H82E2) at 1 ug/mL (100 uL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 ug/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.2-3 ng/mL (QC tested).
Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 ug/mL (100 uL/well) can bind Biotinylated Human HLA-A*11:01&B2M&KRASG12R (VVVGARGVGK) Complex Protein (Cat. No. HLR-H82E2) with a linear range of 0.1-4 ng/mL (Routinely tested).