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Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Monomer, MALS verified)

Product Sizes
25 ug
£180.00
HLN-H82E7-25UG
200 ug
£707.00
HLN-H82E7-200UG
About this Product
SKU:
HLN-H82E7
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
The HLA-A*02:01&B2M&Survivin (LTLGEFLKL) complex is a key antigen-presenting complex in the immune system. HLA-A*02:01, a major histocompatibility complex (MHC) class I molecule, forms a stable heterodimer with B Beta2-microglobulin (B2M). Subsequently, this dimer binds to the Survivin-derived peptide LTLGEFLKL-a specific epitope of Survivin, an anti-apoptotic protein overexpressed in various tumors. This complex is critical for activating cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells expressing Survivin.
Immunogen:
HLA-A*0201 & B2M & Survivin (LTLGEFLKL)
Molecular Weight:
36.3 kDa and 11.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Anti-HLA class I Antibody, Human IgG1 (W6/32) at 1 ug/mL (100 uL/well) can bind Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Cat. No. HLN-H82E7) with a linear range of 0.2-4 ng/mL (QC tested).
Immobilized Anti-B2M Antibody, Human IgG1 at 1 ug/mL (100 uL/well) can bind Biotinylated Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Complex Protein (Cat. No. HLN-H82E7) with a linear range of 0.1-4 ng/mL (Routinely tested).