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APC-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQCFL) Tetramer Protein

Product Sizes
25 ug
£424.00
HL1-HA2H4-25UG
200 ug
£2426.00
HL1-HA2H4-200UG
About this Product
SKU:
HL1-HA2H4
Buffer:
PBS, 1% BSA, pH7.4
Conjugate:
APC
Extra Details:
NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A2 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients. The Human HLA-A*0201 NY-ESO-1 (SLLMWITQCFL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and SLLMWITQCFL peptide of the NY-ESO-1.
Immunogen:
HLA-A*0201 & B2M & NY-ESO-1 (SLLMWITQCFL)
Molecular Weight:
36.3 kDa and 11.7 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
Please refer to datasheet
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Immobilized APC-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQCFL) Tetramer Protein (Cat. No. HL1-HA2H4) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-HLA class I Antibody, Human IgG1 (W632) with a linear range of 0.1-3 ng/mL (QC tested).
Immobilized APC-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQCFL) Tetramer Protein (Cat. No. HL1-HA2H4) at 1 ug/mL (100 uL/well) can bind Monoclonal Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-3 ng/mL (Routinely tested).