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Proteins and Peptides

Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (MALS & SPR verified)

Product Sizes
25 ug
£307.00
HL1-H52E8-25UG
200 ug
£1867.00
HL1-H52E8-200UG
About this Product
SKU:
HL1-H52E8
Additional Names:
HLA-A*02:01 & B2M & NY-ESO-1
Buffer:
PBS
Extra Details:
NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A2 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients. The Human HLA-A*0201 NY-ESO-1 (SLLMWITQC) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and SLLMWITQC peptide of the NY-ESO-1.
Immunogen:
HLA-A*02:01 & B2M & NY-ESO-1 (SLLMWITQC)
Molecular Weight:
36.3 kDa, 13.8 kDa and 13.3 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (Cat. No. HL1-H52E8) at 5 ug/mL (100 uL/well) can bind Anti-NY-ESO-1 Antibody, Human IgG1 with a linear range of 0.001-0.313 ug/mL (QC tested).
Immobilized Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (Cat. No. HL1-H52E8) at 1 ug/mL (100 uL/well) can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL (Routinely tested).