Mouse GUCY2C / Guanylyl cyclase C Protein, His Tag (MALS verified)
Product Sizes
100 ug
£371.00
GUC-M52H3-100UG
1 mg
£2697.00
GUC-M52H3-1MG
About this Product
- SKU:
- GUC-M52H3
- Additional Names:
- GC-C|GUC2C|GUCY2C|hSTAR|STA receptor|STAR
- Buffer:
- PBS
- Extra Details:
- GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
- Immunogen:
- GUCY2C
- Molecular Weight:
- 49.0 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
