Biotinylated Mouse GUCY2C / Guanylyl cyclase C Protein, His,Avitag[TM]
Product Sizes
25 ug
£377.00
GUC-M52E5-25UG
200 ug
£1466.00
GUC-M52E5-200UG
About this Product
- SKU:
- GUC-M52E5
- Buffer:
- PBS
- Conjugate:
- Biotin
- Extra Details:
- GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.
- Immunogen:
- GUCY2C
- Molecular Weight:
- 50.7 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
