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Proteins and Peptides

Human GM-CSF R alpha Protein, Fc Tag

Product Sizes
100 ug
£348.00
GRA-H5255-100UG
1 mg
£2456.00
GRA-H5255-1MG
About this Product
SKU:
GRA-H5255
Additional Names:
CD116|CDw116|CSF2R|CSF2RA|CSF2RY|GM-CSF R alpha|GM-CSF-R-alpha|GMCSFR-alpha|GMR-alpha
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Extra Details:
GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor A Alpha-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.
Immunogen:
GM-CSF R alpha
Molecular Weight:
60.9 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Human GM-CSF R alpha, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Immobilized Human GM-CSF, premium grade (Cat. No. GMF-H4214) at 1 ug/mL (100 uL/well) can bind Human GM-CSF R alpha, Fc Tag (Cat. No. GRA-H5255) with a linear range of 0.5-16 ng/mL (QC tested).