Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Proteins and Peptides

Human GPRC5D Full Length Protein, Flag,His Tag (Detergent)

Product Sizes
20 ug
£1419.00
GPD-H52D5-20UG
100 ug
£3674.00
GPD-H52D5-100UG
500 ug
£8319.00
GPD-H52D5-500UG
About this Product
SKU:
GPD-H52D5
Buffer:
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Extra Details:
GPRC5D is an orphan G protein-coupled receptor (GPCR) with highly restricted expression in hair follicles, yet it is specifically and uniformly overexpressed on malignant plasma cells in multiple myeloma (MM). This unique expression profile makes it an ideal immunotherapy target, leading to the development of approved bispecific antibodies like talquetamab and promising CAR-T therapies for MM
Immunogen:
GPRC5D
Molecular Weight:
37.9 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Immobilized Human GPRC5D Full Length Protein, Flag,His Tag (Cat. No. GPD-H52D5) at 1 ug/mL (100 uL/well) can bind Anti-GPRC5D Antibody, Human IgG4 with a linear range of 0.5-16 ng/mL (QC tested).
Immobilized Human GPRC5D Full Length Protein, Flag,His Tag (Cat. No. GPD-H52D5) at 1 ug/mL, add Talquetamab and then add Biotinylated Human CD3E&CD3G Heterodimer Protein, His,Avitag&Tag Free (Cat. No. CDG-H82W3) at 5 ug/mL. Detection was performed using HRP-conjugated Streptavidin (Cat. No. STN-NH913) (Routinely tested).