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Biotinylated Rhesus macaque Glypican 2 / GPC2 Protein, His,Avitag[TM] (MALS verified)

Product Sizes
25 ug
£360.00
GP2-R82E3-25UG
200 ug
£1425.00
GP2-R82E3-200UG
About this Product
SKU:
GP2-R82E3
Buffer:
PBS
Conjugate:
Biotin
Extra Details:
Glypican 2 (GPC2), also known cerebroglycan, is a glycophosphatidylinositol-linked integral membrane heparan sulfate proteoglycan found in the developing nervous system. Cerebroglycan participates in cell adhesion and is thought to regulate the growth and guidance of axons. Cerebroglycan has especially high affinity for laminin-1. GPC2 silencing inactivates Wnt/B Beta-catenin signaling and reduces the expression of N-Myc, an oncogenic driver of neuroblastoma tumorigenesis. Immunotoxins and chimeric antigen receptor (CAR) T cells targeting GPC2 inhibit neuroblastoma growth in mouse models. A GPC3 specific antibody drug conjugate (ADC) can also inhibit neuroblastoma cell proliferation.
Immunogen:
Glypican 2
Molecular Weight:
61.6 kda
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
Biotinylated Rhesus macaque Glypican 2 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized Human Midkine Protein, premium grade (Cat. No. MIE-H5117) at 5 ug/mL (100 uL/well) can bind Biotinylated Rhesus macaque Glypican 2 Protein, His,Avitag (Cat. No. GP2-R82E3) with a linear range of 0.001-0.5 ug/mL (QC tested).