GMP Human IL-18 Protein
Product Sizes
50 ug
£1225.00
GMP-L18H16-50UG
1 mg
£9762.00
GMP-L18H16-1MG
10 mg
£82025.00
GMP-L18H16-10MG
About this Product
- SKU:
- GMP-L18H16
- Buffer:
- PBS
- Extra Details:
- Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-G Gamma (IFN-G Gamma) production from T helper type 1 (Th1) cells and natural killer (NK) cells, particularly in the presence of IL-12. IL-18 also participates in the developmental regulation of Th1 cells and mediates Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for the treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. IL-18 exerts its biological functions by inducing heterodimerization of the two subunits of its receptor, IL-18RA Alpha and IL-18RB Beta. These subunits share structural homology with members of the IL-1 receptor superfamily.
- Immunogen:
- IL-18
- Molecular Weight:
- 18.2 kDa
- Physical State:
- Powder
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
