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Proteins and Peptides

Human GLP1R Full Length Protein (L260F), Flag,His Tag (Detergent)

Product Sizes
20 ug
£1419.00
GLR-H52D4-20UG
100 ug
£3674.00
GLR-H52D4-100UG
500 ug
£8319.00
GLR-H52D4-500UG
About this Product
SKU:
GLR-H52D4
Buffer:
50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5
Extra Details:
This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
Immunogen:
GLP1R
Molecular Weight:
66.5 kDa
Physical State:
Liquid
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
Immobilized Human GLP1R Full Length Protein, Flag,His Tag (Cat. No. GLR-H52D4) at 5 ug/mL (100 uL/well) on a Nickel Coated plate (Cat. No. SP-16) can bind Dulaglutide with a linear range of 0.5-16 ng/mL (QC tested).
Immobilized Human GLP1R Full Length Protein (L260F), Flag,His Tag (Cat. No. GLR-H52D4) at 5 ug/mL (100 uL/well) can bind Glutazumab with a linear range of 0.06-1 ng/mL (Routinely tested).