Monoclonal Anti-Human Cytomegalovirus (strain AD169) Glycoprotein H&L&O Antibody, Human IgG1 (2B1) (MALS verified)
Product Sizes
100 ug
£371.00
GLO-MY2285-100UG
1 mg
£2461.00
GLO-MY2285-1MG
About this Product
- SKU:
- GLO-MY2285
- Buffer:
- PBS (pH 7.4)
- translate.label.attr.clone:
- 2B1
- Clonality:
- Monoclonal
- Extra Details:
- Human cytomegalovirus (HCMV), a prototypical beta-herpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cell-specific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to platelet-derived growth factor-alpha (PDGFRA Alpha). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion.
- Immunogen:
- Glycoprotein H & Glycoprotein L & Glycoprotein O/gH & gL & gO (HCMV)
- Physical State:
- Powder
- Purification:
- 0.95
- Reactivities:
- Mouse
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- ACRO Biosystems
- Type:
- Antibody: Monoclonal Antibody
