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Proteins and Peptides

HHV-5 (strain AD169) Glycoprotein H&L, His Tag (MALS verified)

Product Sizes
50 ug
£825.00
GHL-H5243-50UG
500 ug
£3833.00
GHL-H5243-500UG
About this Product
SKU:
GHL-H5243
Buffer:
PBS
Extra Details:
Human cytomegalovirus (HCMV), a prototypical beta-herpes virus, is a major cause of morbidity and mortality in immunocompromised transplant recipients and congenitally infected fetuses.Different HCMV glycoprotein complexes are capable of meditating entry through interaction with cell-specific receptors on a panel of host cells. The pentamer (gH/gL/UL128/UL130/UL131A) mediates HCMV entry into epithelial, endothelial, and myeloid cells by its binding to neuropilin 2 (Nrp2). The trimer (gH/gL/gO) can mediate infection of all cell types by binding to platelet-derived growth factor-alpha (PDGFRA Alpha). Both pentamer and trimer need to interact with the glycoprotein B (gB), the fusogenic protein, to trigger the virus and host cell membrane fusion.
Immunogen:
Glycoprotein H & Glycoprotein L/gH & gL (HCMV)
Molecular Weight:
109.5 kDa
Physical State:
Powder
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
HHV-5 (strain AD169) Glycoprotein H&L, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Immobilized HHV-5 (strain AD169) Glycoprotein H&L, His Tag (Cat. No. GHL-H5243) at 1 ug/mL (100 uL/well) can bind Anti-HCMV gH [HCMV16], Human, IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Immobilized Anti-HCMV gH [HCMV16], Human, IgG1 at 1 ug/mL (100 uL/well) can bind HHV-5 (strain AD169) Glycoprotein H&L, His Tag (Cat. No. GHL-H5243) with a linear range of 0.004-0.25 ug/mL (Routinely tested).